Romero Osby scored 12 points, Amath M'Baye added 11 and Oklahoma led from start to finish in a 75-48 victory against last-place TCU on Monday night.
The Sooners (16-7, 7-4 Big 12) held TCU scoreless for the first eight minutes and extended their lead to 25 by halftime. Oklahoma led by as much as 36 after Andrew Fitzgerald's three-point play to finish a 13-0 run with 13:17 left in the game.
TCU (10-14, 1-10) responded with its only extended stretch of strong play, scoring nine points in a row. But by then it was far too little, too late. Oklahoma led by at least 20 throughout the second half on its way to surpassing last season's win total.
Devonta Abron led TCU with 12 points and Kyan Anderson scored 11 on 4-for-19 shooting.
The Sooners scored the game's first eight points and led 15-1 midway through the first half, forcing the Big 12's worst offense into poor shots, frequently coming late on the shot clock. The Horned Frogs came in rated last in the conference in scoring, shooting percentage, rebounds, steals and blocks and played nowhere near the same level as during a stunning upset of then-No. 5 Kansas last week.
On Saturday, the Sooners got their own win against Kansas, their first upset of a top 5 team since 2006, and followed up on Monday with another strong performance.
The Horned Frogs missed their first 14 shots, including a pair of air balls, and didn't get on the scoreboard until Adrick McKinney hit one of two free throws with 11:52 left before halftime. Their first basket didn't go in until Connell Crossland scored inside with 8:49 left in the first half.
TCU missed 20 of its 24 shots in the first half while falling behind 36-11.